{"product_id":"renue-by-science-trigonelline-250mg-nad-support-90-capsules","title":"Renue By Science Trigonelline 250mg NAD+ Support - 90 Capsules","description":"\u003cp\u003eRenue By Science Trigonelline is a high-strength NAD+ precursor supplement designed to support cellular energy production and longevity. Each capsule delivers 250mg of trigonelline, a naturally occurring compound found in coffee and fenugreek that promotes NAD+ synthesis through the Preiss-Handler pathway.\u003c\/p\u003e\n\u003ch2\u003eKey Features\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSupports muscle NAD+ synthesis and cellular energy production\u003c\/li\u003e\n\u003cli\u003ePromotes DNA repair and healthy gene expression through methyl group donation\u003c\/li\u003e\n\u003cli\u003eProtects heart, brain, and muscle function by replenishing NAD+ in tissues affected by aging\u003c\/li\u003e\n\u003cli\u003eStable through digestion with systemic tissue delivery and no niacin flushing effect\u003c\/li\u003e\n\u003cli\u003eNon-GMO, made in the USA, and third-party tested\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWho Is It For\u003c\/h2\u003e\u003cp\u003eThis supplement suits anyone interested in supporting cellular health, energy metabolism, and longevity as they age. It is particularly relevant for those seeking NAD+ support without the flushing effects associated with traditional niacin supplements.\u003c\/p\u003e\n\u003ch2\u003eProduct Details\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003cth\u003eBrand\u003c\/th\u003e\n\u003ctd\u003eRenue By Science\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003ctd\u003eCapsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSize\u003c\/th\u003e\n\u003ctd\u003e90 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\u003ch3\u003eWhat is trigonelline and how does it support NAD+ levels?\u003c\/h3\u003e\u003cp\u003eTrigonelline is a naturally occurring alkaloid found in coffee and fenugreek. It supports NAD+ synthesis through the Preiss-Handler pathway, providing the precursors needed to generate NAD+ that becomes depleted through cellular metabolism and aging.\u003c\/p\u003e\u003ch3\u003eHow does this product differ from other NAD+ precursors like NMN or NR?\u003c\/h3\u003e\u003cp\u003eUnlike NMN or NR, trigonelline specifically promotes NAD+ synthesis in muscle tissue. It is also stable through digestion, enters circulation for systemic tissue delivery, and does not cause the flushing effect that many experience with niacin.\u003c\/p\u003e\u003ch3\u003eCan trigonelline cross the blood-brain barrier?\u003c\/h3\u003e\u003cp\u003eYes, trigonelline is highly bioavailable and can cross the blood-brain barrier, allowing it to support NAD+ levels in brain tissue and help preserve cognitive function.\u003c\/p\u003e\u003ch3\u003eIs this product third-party tested?\u003c\/h3\u003e\u003cp\u003eYes, this trigonelline supplement is third-party tested and non-GMO, made in the USA.\u003c\/p\u003e\n\u003cscript type=\"application\/ld+json\"\u003e{\"@context\": \"https:\/\/schema.org\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"What is trigonelline and how does it support NAD+ levels?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Trigonelline is a naturally occurring alkaloid found in coffee and fenugreek. It supports NAD+ synthesis through the Preiss-Handler pathway, providing the precursors needed to generate NAD+ that becomes depleted through cellular metabolism and aging.\"}}, {\"@type\": \"Question\", \"name\": \"How does this product differ from other NAD+ precursors like NMN or NR?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Unlike NMN or NR, trigonelline specifically promotes NAD+ synthesis in muscle tissue. It is also stable through digestion, enters circulation for systemic tissue delivery, and does not cause the flushing effect that many experience with niacin.\"}}, {\"@type\": \"Question\", \"name\": \"Can trigonelline cross the blood-brain barrier?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Yes, trigonelline is highly bioavailable and can cross the blood-brain barrier, allowing it to support NAD+ levels in brain tissue and help preserve cognitive function.\"}}, {\"@type\": \"Question\", \"name\": \"Is this product third-party tested?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Yes, this trigonelline supplement is third-party tested and non-GMO, made in the USA.\"}}]}\u003c\/script\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":67652862935294,"sku":"P-126530","price":128.0,"currency_code":"CAD","in_stock":true}],"url":"https:\/\/vitaminnorth.com\/products\/renue-by-science-trigonelline-250mg-nad-support-90-capsules","provider":"VitaminNorth","version":"1.0","type":"link"}